[RETRACTED] ​ASSOCIATION BETWEEN CEREBRAL SMALL VESSEL DISEASE AND RISK OF RECURRENT ICH AMONG U.S. MINORITY SURVIVORS

by Priyanka Senthil

​Category: STEM

RETRACTION NOTICE - Upon receiving multiple reports from researchers not affiliated with the IYRC, as well as a subsequent investigation by our editorial team, we have retracted Priyanka Senthil's paper and presentation for duplication and plagiarism. The IYRC has zero tolerance for plagiarism and other academic misconduct. Senthil has acknowledged the retraction and co-author Dr. Alessandro Biffi has been contacted.

Abstract – Introduction: Compared to White survivors of Intracerebral Hemorrhage (ICH), Black/Hispanic individuals are three times more likely to experience ICH recurrence. Cerebral Small Vessel Disease (CSVD) has long been considered a risk factor for ICH. Our study sought to clarify whether differences in CSVD subtype or severity among minority and White individuals could explain this disparity. Methods: We collected data of ICH survivors from the MGH-ICH and ERICH studies. MRI scans were analyzed for CSVD markers as classified by cerebral microbleeds (CMBs). CSVD was identified as either Cerebral Amyloid Angiopathy (CAA) subtype or Arteriolo-Sclerosis (AS) subtype. Results: We analyzed data from the total 2192. When compared to Whites, a higher percentage of minority individuals had markers of CSVD on MRI scans (54% vs. 41%, p<0.001). There was a greater count (higher burden) of AS-associated CMBs in minorities (median: 1, IQR 1-2 vs. median 0, IQR 0-1, p=0.016). Conclusion: Minority ICH survivors are not only more likely to present with CSVD at the time of stroke, but they also have a higher burden of specifically associated CMBs.